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We conducted a large-scale, multicenter, cross-sectional seroepidemiologic household transmission study in southwest Germany during May 11–August 1, 2020. Resolving the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in households with members from different generations is crucial for containing the current pandemic. Our findings can help jurisdictions allocate resources for contact tracing. Contact tracing reduced the number of cases between contact generations and time between symptom onset and investigation but required substantial resources. Median time from symptom onset to investigation was 7 days for index cases and 4 days for first-generation contacts. At initial interview, 51% (187/370) of contacts were COVID-19–positive 35% (98/277) became positive during 14-day quarantine. Among contacts, 374 (25%) had COVID-19 secondary case detection rate was ≈31% among first-generation contacts, ≈16% among second- and third-generation contacts, and ≈12% among fourth-, fifth-, and sixth-generation contacts. We estimated 1,102 staff hours and $29,234 spent investigating index cases and contacts. During March–May 2020, we constructed transmission chains from 184 index cases and 1,499 contacts in Salt Lake County, Utah, USA, to assess outcomes and estimate staff time and salaries. Outcomes and costs of coronavirus disease (COVID-19) contact tracing are limited. Emerging Infectious Diseases, 27(12), 2988-2998.Ĭoronavirus Disease Contact Tracing Outcomes and Cost, Salt Lake County, Utah, USA, March–May 2020 Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020. Keita, M., Lucaccioni, H., Ilumbulumbu, M., Polonsky, J., Nsio-Mbeta, J., Panda, G.Ahuka-Mundeke, S. Keita M, Lucaccioni H, Ilumbulumbu M, et al. Keita M, Lucaccioni H, Ilumbulumbu M, Polonsky J, Nsio-Mbeta J, Panda G, et al.